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The H29D Mutation Does Not Enhance Cytosolic Ca(2+) Activation of the Cardiac Ryanodine Receptor
The N-terminal domain of the cardiac ryanodine receptor (RyR2) harbors a large number of naturally occurring mutations that are associated with stress-induced ventricular tachyarrhythmia and sudden death. Nearly all these disease-associated N-terminal mutations are located at domain interfaces or bu...
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| Izdano u: | PLoS One |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4583508/ https://ncbi.nlm.nih.gov/pubmed/26405799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139058 |
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