Roles of the NH(2)-terminal Domains of Cardiac Ryanodine Receptor in Ca(2+) Release Activation and Termination

The NH(2)-terminal region (residues 1–543) of the cardiac ryanodine receptor (RyR2) harbors a large number of mutations associated with cardiac arrhythmias and cardiomyopathies. Functional studies have revealed that the NH(2)-terminal region is involved in the activation and termination of Ca(2+) re...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Liu, Yingjie, Sun, Bo, Xiao, Zhichao, Wang, Ruiwu, Guo, Wenting, Zhang, Joe Z., Mi, Tao, Wang, Yundi, Jones, Peter P., Van Petegem, Filip, Chen, S. R. Wayne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367275/
https://ncbi.nlm.nih.gov/pubmed/25627681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.618827
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