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Roles of the NH(2)-terminal Domains of Cardiac Ryanodine Receptor in Ca(2+) Release Activation and Termination
The NH(2)-terminal region (residues 1–543) of the cardiac ryanodine receptor (RyR2) harbors a large number of mutations associated with cardiac arrhythmias and cardiomyopathies. Functional studies have revealed that the NH(2)-terminal region is involved in the activation and termination of Ca(2+) re...
Guardat en:
| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4367275/ https://ncbi.nlm.nih.gov/pubmed/25627681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.618827 |
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