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A role of uridylation pathway for blockade of let-7 microRNA biogenesis by Lin28B
The precise control of microRNA (miRNA) biosynthesis is crucial for gene regulation. Lin28A and Lin28B are selective inhibitors of biogenesis of let-7 miRNAs involved in development and tumorigenesis. Lin28A selectively inhibits let-7 biogenesis through cytoplasmic uridylation of precursor let-7 by...
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| Publicado en: | Cancer Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4582986/ https://ncbi.nlm.nih.gov/pubmed/26080928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12721 |
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