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A role of uridylation pathway for blockade of let-7 microRNA biogenesis by Lin28B

The precise control of microRNA (miRNA) biosynthesis is crucial for gene regulation. Lin28A and Lin28B are selective inhibitors of biogenesis of let-7 miRNAs involved in development and tumorigenesis. Lin28A selectively inhibits let-7 biogenesis through cytoplasmic uridylation of precursor let-7 by...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Sci
Main Authors: Suzuki, Hiroshi I, Katsura, Akihiro, Miyazono, Kohei
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582986/
https://ncbi.nlm.nih.gov/pubmed/26080928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12721
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