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Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission

The focal adhesion protein vinculin connects the actin cytoskeleton, through talin and integrins, with the extracellular matrix. Vinculin consists of a globular head and tail domain, which undergo conformational changes from a closed auto-inhibited conformation in the cytoplasm to an open conformati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Sci
Egile Nagusiak: Auernheimer, Vera, Lautscham, Lena A., Leidenberger, Maria, Friedrich, Oliver, Kappes, Barbara, Fabry, Ben, Goldmann, Wolfgang H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582403/
https://ncbi.nlm.nih.gov/pubmed/26240176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.172031
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