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Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission

The focal adhesion protein vinculin connects the actin cytoskeleton, through talin and integrins, with the extracellular matrix. Vinculin consists of a globular head and tail domain, which undergo conformational changes from a closed auto-inhibited conformation in the cytoplasm to an open conformati...

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Podrobná bibliografie
Vydáno v:J Cell Sci
Hlavní autoři: Auernheimer, Vera, Lautscham, Lena A., Leidenberger, Maria, Friedrich, Oliver, Kappes, Barbara, Fabry, Ben, Goldmann, Wolfgang H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582403/
https://ncbi.nlm.nih.gov/pubmed/26240176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.172031
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