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Vinculin Phosphorylation at Tyr(1065) Regulates Vinculin Conformation and Tension Development in Airway Smooth Muscle Tissues
Vinculin localizes to membrane adhesion junctions in smooth muscle tissues, where its head domain binds to talin and its tail domain binds to filamentous actin, thus linking actin filaments to the extracellular matrix. Vinculin can assume a closed conformation, in which the head and tail domains bin...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3916566/ https://ncbi.nlm.nih.gov/pubmed/24338477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.508077 |
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