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The Phosphorylation of Vinculin on Tyrosine Residues 100 and 1065, Mediated by Src Kinases, Affects Cell Spreading

Vinculin is a conserved actin binding protein localized in focal adhesions and cell-cell junctions. Here, we report that vinculin is tyrosine phosphorylated in platelets spread on fibrinogen and that the phosphorylation is Src kinases dependent. The phosphorylation of vinculin on tyrosine was recons...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Zhiyong, Izaguirre, Gonzalo, Lin, Siang-Yo, Lee, Hwa Young, Schaefer, Erik, Haimovich, Beatrice
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC515355/
https://ncbi.nlm.nih.gov/pubmed/15229287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-03-0264
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