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The Phosphorylation of Vinculin on Tyrosine Residues 100 and 1065, Mediated by Src Kinases, Affects Cell Spreading

Vinculin is a conserved actin binding protein localized in focal adhesions and cell-cell junctions. Here, we report that vinculin is tyrosine phosphorylated in platelets spread on fibrinogen and that the phosphorylation is Src kinases dependent. The phosphorylation of vinculin on tyrosine was recons...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Zhiyong, Izaguirre, Gonzalo, Lin, Siang-Yo, Lee, Hwa Young, Schaefer, Erik, Haimovich, Beatrice
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC515355/
https://ncbi.nlm.nih.gov/pubmed/15229287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-03-0264
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