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Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission
The focal adhesion protein vinculin connects the actin cytoskeleton, through talin and integrins, with the extracellular matrix. Vinculin consists of a globular head and tail domain, which undergo conformational changes from a closed auto-inhibited conformation in the cytoplasm to an open conformati...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4582403/ https://ncbi.nlm.nih.gov/pubmed/26240176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.172031 |
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