Defining the three cell lineages of the human blastocyst by single-cell RNA-seq

Here, we provide fundamental insights into early human development by single-cell RNA-sequencing of human and mouse preimplantation embryos. We elucidate conserved transcriptional programs along with those that are human specific. Importantly, we validate our RNA-sequencing findings at the protein l...

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Detalles Bibliográficos
Publicado en:Development
Autores principales: Blakeley, Paul, Fogarty, Norah M. E., del Valle, Ignacio, Wamaitha, Sissy E., Hu, Tim Xiaoming, Elder, Kay, Snell, Philip, Christie, Leila, Robson, Paul, Niakan, Kathy K.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists 2015
Materias:
Stem Cells and Regeneration
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582176/
https://ncbi.nlm.nih.gov/pubmed/26293300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.123547
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