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Conversion from mouse embryonic to extra-embryonic endoderm stem cells reveals distinct differentiation capacities of pluripotent stem cell states

The inner cell mass of the mouse pre-implantation blastocyst comprises epiblast progenitor and primitive endoderm cells of which cognate embryonic (mESCs) or extra-embryonic (XEN) stem cell lines can be derived. Importantly, each stem cell type retains the defining properties and lineage restriction...

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Detalhes bibliográficos
Main Authors: Cho, Lily T. Y., Wamaitha, Sissy E., Tsai, Isheng J., Artus, Jérôme, Sherwood, Richard I., Pedersen, Roger A., Hadjantonakis, Anna-Katerina, Niakan, Kathy K.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403099/
https://ncbi.nlm.nih.gov/pubmed/22791892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.078519
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