Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells

Transcription factor-mediated reprograming is a powerful method to study cell fate changes. In this study, we demonstrate that the transcription factor Gata6 can initiate reprograming of multiple cell types to induced extraembryonic endoderm stem (iXEN) cells. Intriguingly, Gata6 is sufficient to dr...

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Veröffentlicht in:Genes Dev
Hauptverfasser: Wamaitha, Sissy E., del Valle, Ignacio, Cho, Lily T.Y., Wei, Yingying, Fogarty, Norah M.E., Blakeley, Paul, Sherwood, Richard I., Ji, Hongkai, Niakan, Kathy K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495396/
https://ncbi.nlm.nih.gov/pubmed/26109048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.257071.114
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