Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells

Transcription factor-mediated reprograming is a powerful method to study cell fate changes. In this study, we demonstrate that the transcription factor Gata6 can initiate reprograming of multiple cell types to induced extraembryonic endoderm stem (iXEN) cells. Intriguingly, Gata6 is sufficient to dr...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Wamaitha, Sissy E., del Valle, Ignacio, Cho, Lily T.Y., Wei, Yingying, Fogarty, Norah M.E., Blakeley, Paul, Sherwood, Richard I., Ji, Hongkai, Niakan, Kathy K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495396/
https://ncbi.nlm.nih.gov/pubmed/26109048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.257071.114
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