mTOR activity paces human blastocyst stage developmental progression

Many mammals can temporally uncouple conception from parturition by pacing down their development around the blastocyst stage. In mice, this dormant state is achieved by decreasing the activity of the growth-regulating mTOR signaling pathway. It is unknown whether this ability is conserved in mammal...

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Publicado en:Cell
Main Authors: Iyer, Dhanur P., Khoei, Heidar Heidari, van der Weijden, Vera A., Kagawa, Harunobu, Pradhan, Saurabh J., Novatchkova, Maria, McCarthy, Afshan, Rayon, Teresa, Simon, Claire S., Dunkel, Ilona, Wamaitha, Sissy E., Elder, Kay, Snell, Phil, Christie, Leila, Schulz, Edda G., Niakan, Kathy K., Rivron, Nicolas, Bulut-Karslioğlu, Aydan
Formato: Artigo
Idioma:Inglês
Publicado: 2024
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617234/
https://ncbi.nlm.nih.gov/pubmed/39332412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2024.08.048
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