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Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM
Immunoglobulins M (IgMs) are gaining increasing attention as biopharmaceuticals since their multivalent mode of binding can give rise to high avidity. Furthermore, IgMs are potent activators of the complement system. However, they are frequently difficult to express recombinantly and can suffer from...
में बचाया:
| में प्रकाशित: | Biochim Biophys Acta |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Elsevier Pub. Co
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4582045/ https://ncbi.nlm.nih.gov/pubmed/25748881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2015.02.018 |
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