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Germinality does not necessarily define mAb expression and thermal stability

The production potential of recombinant monoclonal antibody (mAb) expressing cell lines depends, among other factors, on the intrinsic antibody structure determined by the amino acid sequence. In this study, we investigated the influence of somatic mutations in the V(D)J sequence of four individual,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Appl Microbiol Biotechnol
Egile Nagusiak: Schwaigerlehner, Linda, Mayrhofer, Patrick, Diem, Matthias, Steinfellner, Willibald, Fenech, Emma, Oostenbrink, Chris, Kunert, Renate
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719414/
https://ncbi.nlm.nih.gov/pubmed/31350616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-019-09998-3
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