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Krüppel expression levels are maintained through compensatory evolution of shadow enhancers

Many developmental genes are controlled by shadow enhancers, pairs of enhancers that drive overlapping expression patterns. We hypothesized that compensatory evolution can maintain the total expression of a gene while individual shadow enhancers diverge between species. To test this hypothesis, we a...

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Bibliografische gegevens
Gepubliceerd in:Cell Rep
Hoofdauteurs: Wunderlich, Zeba, Bragdon, Meghan D.J., Vincent, Ben J., White, Jonathan A., Estrada, Javier, DePace, Angela H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581983/
https://ncbi.nlm.nih.gov/pubmed/26344774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.021
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