Shadow enhancers enable Hunchback bifunctionality in the Drosophila embryo

Hunchback (Hb) is a bifunctional transcription factor that activates and represses distinct enhancers. Here, we investigate the hypothesis that Hb can activate and repress the same enhancer. Computational models predicted that Hb bifunctionally regulates the even-skipped (eve) stripe 3+7 enhancer (e...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Staller, Max V., Vincent, Ben J., Bragdon, Meghan D. J., Lydiard-Martin, Tara, Wunderlich, Zeba, Estrada, Javier, DePace, Angela H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2015
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311800/
https://ncbi.nlm.nih.gov/pubmed/25564665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413877112
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