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Krüppel expression levels are maintained through compensatory evolution of shadow enhancers

Many developmental genes are controlled by shadow enhancers, pairs of enhancers that drive overlapping expression patterns. We hypothesized that compensatory evolution can maintain the total expression of a gene while individual shadow enhancers diverge between species. To test this hypothesis, we a...

詳細記述

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書誌詳細
出版年:Cell Rep
主要な著者: Wunderlich, Zeba, Bragdon, Meghan D.J., Vincent, Ben J., White, Jonathan A., Estrada, Javier, DePace, Angela H.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581983/
https://ncbi.nlm.nih.gov/pubmed/26344774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.021
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