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Inhibition of Phosphatidylcholine-Specific Phospholipase C Interferes with Proliferation and Survival of Tumor Initiating Cells in Squamous Cell Carcinoma

PURPOSE: The role of phosphatidylcholine-specific phospholipase C (PC-PLC), the enzyme involved in cell differentiation and proliferation, has not yet been explored in tumor initiating cells (TICs). We investigated PC-PLC expression and effects of PC-PLC inhibition in two adherent (AD) squamous carc...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Cecchetti, Serena, Bortolomai, Ileana, Ferri, Renata, Mercurio, Laura, Canevari, Silvana, Podo, Franca, Miotti, Silvia, Iorio, Egidio
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581859/
https://ncbi.nlm.nih.gov/pubmed/26402860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136120
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