Activation of Phosphatidylcholine-Specific Phospholipase C in Breast and Ovarian Cancer: Impact on MRS-Detected Choline Metabolic Profile and Perspectives for Targeted Therapy

Elucidation of molecular mechanisms underlying the aberrant phosphatidylcholine cycle in cancer cells plays in favor of the use of metabolic imaging in oncology and opens the way for designing new targeted therapies. The anomalous choline metabolic profile detected in cancer by magnetic resonance sp...

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Detalles Bibliográficos
Publicado en:Front Oncol
Autores principales: Podo, Franca, Paris, Luisa, Cecchetti, Serena, Spadaro, Francesca, Abalsamo, Laura, Ramoni, Carlo, Ricci, Alessandro, Pisanu, Maria Elena, Sardanelli, Francesco, Canese, Rossella, Iorio, Egidio
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
Materias:
Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969288/
https://ncbi.nlm.nih.gov/pubmed/27532027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00171
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