Activation of Phosphatidylcholine-Specific Phospholipase C in Breast and Ovarian Cancer: Impact on MRS-Detected Choline Metabolic Profile and Perspectives for Targeted Therapy

Elucidation of molecular mechanisms underlying the aberrant phosphatidylcholine cycle in cancer cells plays in favor of the use of metabolic imaging in oncology and opens the way for designing new targeted therapies. The anomalous choline metabolic profile detected in cancer by magnetic resonance sp...

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Bibliografski detalji
Izdano u:Front Oncol
Glavni autori: Podo, Franca, Paris, Luisa, Cecchetti, Serena, Spadaro, Francesca, Abalsamo, Laura, Ramoni, Carlo, Ricci, Alessandro, Pisanu, Maria Elena, Sardanelli, Francesco, Canese, Rossella, Iorio, Egidio
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Oncology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969288/
https://ncbi.nlm.nih.gov/pubmed/27532027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00171
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