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Retinal Pigment Epithelial Cell Death by the Alternative Complement Cascade: Role of Membrane Regulatory Proteins, Calcium, PKC, and Oxidative Stress
PURPOSE. Retinal pigment epithelial (RPE) cell death is an important feature of the advanced forms of AMD. Complement alternative pathway (AP) activation is associated with RPE cell death in AMD. In this study, we developed a new model to initiate AP activation on RPE cells and investigated the cell...
Zapisane w:
| Wydane w: | Invest Ophthalmol Vis Sci |
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| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Association for Research in Vision and Ophthalmology
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4581691/ https://ncbi.nlm.nih.gov/pubmed/24677108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13554 |
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