Retinal Pigment Epithelial Cell Death by the Alternative Complement Cascade: Role of Membrane Regulatory Proteins, Calcium, PKC, and Oxidative Stress

PURPOSE. Retinal pigment epithelial (RPE) cell death is an important feature of the advanced forms of AMD. Complement alternative pathway (AP) activation is associated with RPE cell death in AMD. In this study, we developed a new model to initiate AP activation on RPE cells and investigated the cell...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Invest Ophthalmol Vis Sci
Egile Nagusiak: Yang, Ping, Baciu, Peter, Kerrigan, Brittany C. Parker, Etheridge, Menna, Sung, Eric, Toimil, Brett A., Berchuck, Jacob E., Jaffe, Glenn J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Association for Research in Vision and Ophthalmology 2014
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581691/
https://ncbi.nlm.nih.gov/pubmed/24677108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13554
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