Wird geladen...

Coupling Protein Side-Chain and Backbone Flexibility Improves the Re-design of Protein-Ligand Specificity

Interactions between small molecules and proteins play critical roles in regulating and facilitating diverse biological functions, yet our ability to accurately re-engineer the specificity of these interactions using computational approaches has been limited. One main difficulty, in addition to inac...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Ollikainen, Noah, de Jong, René M., Kortemme, Tanja
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580623/
https://ncbi.nlm.nih.gov/pubmed/26397464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004335
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!