Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat

The pharmaceutical reactivation of dormant HIV-1 proviruses by histone deacetylase inhibitors (HDACi) represents a possible strategy to reduce the reservoir of HIV-1-infected cells in individuals treated with suppressive combination antiretroviral therapy (cART). However, the effects of such latency...

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Publicado en:J Virol
Autores principales: Olesen, Rikke, Vigano, Selena, Rasmussen, Thomas A., Søgaard, Ole S., Ouyang, Zhengyu, Buzon, Maria, Bashirova, Arman, Carrington, Mary, Palmer, Sarah, Brinkmann, Christel R., Yu, Xu G., Østergaard, Lars, Tolstrup, Martin, Lichterfeld, Mathias
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580197/
https://ncbi.nlm.nih.gov/pubmed/26223643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01484-15
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