Activation of Latent Human Immunodeficiency Virus by the Histone Deacetylase Inhibitor Panobinostat: A Pilot Study to Assess Effects on the Central Nervous System

In a substudy of a clinical trial, we assessed whether activation of latent human immunodeficiency virus (HIV) by the histone deacetylase inhibitor panobinostat had detrimental effects on the central nervous system (CNS). Adults infected with HIV received oral panobinostat 20 mg 3 times per week eve...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Rasmussen, Thomas A., Tolstrup, Martin, Møller, Holger Jon, Brinkmann, Christel R., Olesen, Rikke, Erikstrup, Christian, Laursen, Alex L., Østergaard, Lars, Søgaard, Ole S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438909/
https://ncbi.nlm.nih.gov/pubmed/26034779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofv037
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