Enhanced Influenza Virus-Like Particle Vaccination with a Structurally Optimized RIG-I Agonist as Adjuvant

The molecular interaction between viral RNA and the cytosolic sensor RIG-I represents the initial trigger in the development of an effective immune response against infection with RNA viruses, resulting in innate immune activation and subsequent induction of adaptive responses. In the present study,...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Beljanski, Vladimir, Chiang, Cindy, Kirchenbaum, Greg A., Olagnier, David, Bloom, Chalise E., Wong, Terianne, Haddad, Elias K., Trautmann, Lydie, Ross, Ted M., Hiscott, John
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580177/
https://ncbi.nlm.nih.gov/pubmed/26269188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01526-15
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