Enhanced Influenza Virus-Like Particle Vaccination with a Structurally Optimized RIG-I Agonist as Adjuvant

The molecular interaction between viral RNA and the cytosolic sensor RIG-I represents the initial trigger in the development of an effective immune response against infection with RNA viruses, resulting in innate immune activation and subsequent induction of adaptive responses. In the present study,...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Beljanski, Vladimir, Chiang, Cindy, Kirchenbaum, Greg A., Olagnier, David, Bloom, Chalise E., Wong, Terianne, Haddad, Elias K., Trautmann, Lydie, Ross, Ted M., Hiscott, John
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580177/
https://ncbi.nlm.nih.gov/pubmed/26269188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01526-15
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