Enhanced Influenza Virus-Like Particle Vaccination with a Structurally Optimized RIG-I Agonist as Adjuvant

The molecular interaction between viral RNA and the cytosolic sensor RIG-I represents the initial trigger in the development of an effective immune response against infection with RNA viruses, resulting in innate immune activation and subsequent induction of adaptive responses. In the present study,...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Beljanski, Vladimir, Chiang, Cindy, Kirchenbaum, Greg A., Olagnier, David, Bloom, Chalise E., Wong, Terianne, Haddad, Elias K., Trautmann, Lydie, Ross, Ted M., Hiscott, John
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580177/
https://ncbi.nlm.nih.gov/pubmed/26269188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01526-15
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