Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists

The cytosolic RIG-I (retinoic acid-inducible gene I) receptor plays a pivotal role in the initiation of the immune response against RNA virus infection by recognizing short 5′-triphosphate (5′ppp)-containing viral RNA and activating the host antiviral innate response. In the present study, we genera...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Chiang, Cindy, Beljanski, Vladimir, Yin, Kevin, Olagnier, David, Ben Yebdri, Fethia, Steel, Courtney, Goulet, Marie-Line, DeFilippis, Victor R., Streblow, Daniel N., Haddad, Elias K., Trautmann, Lydie, Ross, Ted, Lin, Rongtuan, Hiscott, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505665/
https://ncbi.nlm.nih.gov/pubmed/26018150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00845-15
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