Enhanced Influenza Virus-Like Particle Vaccination with a Structurally Optimized RIG-I Agonist as Adjuvant

The molecular interaction between viral RNA and the cytosolic sensor RIG-I represents the initial trigger in the development of an effective immune response against infection with RNA viruses, resulting in innate immune activation and subsequent induction of adaptive responses. In the present study,...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Beljanski, Vladimir, Chiang, Cindy, Kirchenbaum, Greg A., Olagnier, David, Bloom, Chalise E., Wong, Terianne, Haddad, Elias K., Trautmann, Lydie, Ross, Ted M., Hiscott, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580177/
https://ncbi.nlm.nih.gov/pubmed/26269188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01526-15
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