Enhanced Influenza Virus-Like Particle Vaccination with a Structurally Optimized RIG-I Agonist as Adjuvant

The molecular interaction between viral RNA and the cytosolic sensor RIG-I represents the initial trigger in the development of an effective immune response against infection with RNA viruses, resulting in innate immune activation and subsequent induction of adaptive responses. In the present study,...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Beljanski, Vladimir, Chiang, Cindy, Kirchenbaum, Greg A., Olagnier, David, Bloom, Chalise E., Wong, Terianne, Haddad, Elias K., Trautmann, Lydie, Ross, Ted M., Hiscott, John
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
Onderwerpen:
Vaccines and Antiviral Agents
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580177/
https://ncbi.nlm.nih.gov/pubmed/26269188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01526-15
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