MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links

MERIT40 is an essential component of the RAP80 ubiquitin recognition complex that targets BRCA1 to DNA damage sites. Although this complex is required for BRCA1 foci formation, its physiologic role in DNA repair has remained enigmatic, as has its relationship to canonical DNA repair mechanisms. Surp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Jiang, Qinqin, Paramasivam, Manikandan, Aressy, Bernadette, Wu, Junmin, Bellani, Marina, Tong, Wei, Seidman, Michael M., Greenberg, Roger A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579352/
https://ncbi.nlm.nih.gov/pubmed/26338419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.264192.115
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