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MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links
MERIT40 is an essential component of the RAP80 ubiquitin recognition complex that targets BRCA1 to DNA damage sites. Although this complex is required for BRCA1 foci formation, its physiologic role in DNA repair has remained enigmatic, as has its relationship to canonical DNA repair mechanisms. Surp...
Enregistré dans:
| Publié dans: | Genes Dev |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4579352/ https://ncbi.nlm.nih.gov/pubmed/26338419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.264192.115 |
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