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Mucin Binding Reduces Colistin Antimicrobial Activity

Colistin has found increasing use in treating drug-resistant bacterial lung infections, but potential interactions with pulmonary biomolecules have not been investigated. We postulated that colistin, like aminoglycoside antibiotics, may bind to secretory mucin in sputum or epithelial mucin that line...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Huang, Johnny X., Blaskovich, Mark A. T., Pelingon, Ruby, Ramu, Soumya, Kavanagh, Angela, Elliott, Alysha G., Butler, Mark S., Montgomery, A. Bruce, Cooper, Matthew A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576126/
https://ncbi.nlm.nih.gov/pubmed/26169405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00808-15
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