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Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

[Image: see text] Bacteria have acquired extensive resistance mechanisms to protect themselves against antibiotic action. Today the bacterial membrane has become one of the “final frontiers” in the search for new compounds acting on novel targets to address the threat of multi-drug resistant (MDR) a...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Edwards, Ingrid A., Elliott, Alysha G., Kavanagh, Angela M., Zuegg, Johannes, Blaskovich, Mark A. T., Cooper, Matthew A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906375/
https://ncbi.nlm.nih.gov/pubmed/27331141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00045
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