Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

[Image: see text] Bacteria have acquired extensive resistance mechanisms to protect themselves against antibiotic action. Today the bacterial membrane has become one of the “final frontiers” in the search for new compounds acting on novel targets to address the threat of multi-drug resistant (MDR) a...

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Publicat a:ACS Infect Dis
Autors principals: Edwards, Ingrid A., Elliott, Alysha G., Kavanagh, Angela M., Zuegg, Johannes, Blaskovich, Mark A. T., Cooper, Matthew A.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2016
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906375/
https://ncbi.nlm.nih.gov/pubmed/27331141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00045
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