Fluconazole and Voriconazole Resistance in Candida parapsilosis Is Conferred by Gain-of-Function Mutations in MRR1 Transcription Factor Gene

Candida parapsilosis is the second most prevalent fungal agent causing bloodstream infections. Nevertheless, there is little information about the molecular mechanisms underlying azole resistance in this species. Mutations (G1747A, A2619C, and A3191C) in the MRR1 transcription factor gene were ident...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Branco, Joana, Silva, Ana P., Silva, Raquel M., Silva-Dias, Ana, Pina-Vaz, Cidália, Butler, Geraldine, Rodrigues, Acácio G., Miranda, Isabel M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576118/
https://ncbi.nlm.nih.gov/pubmed/26248365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00842-15
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