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Mechanisms of Acquired In Vivo and In Vitro Resistance to Voriconazole by Candida krusei following Exposure to Suboptimal Drug Concentration

Five Candida krusei isolates (susceptible and resistant) recovered from the urine of a kidney transplant patient treated with voriconazole (VRC) 200 mg twice daily for 20 days were studied. Eight unrelated clinical isolates of C. krusei were exposed in vitro to VRC 0.001 μg/ml for 30 days. Developme...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Ricardo, Elisabete, Grenouillet, Fréderic, Miranda, Isabel M., Silva, Raquel M., Eglin, Guilluame, Devillard, Nadège, Rodrigues, Acácio Gonçalves, Pina-Vaz, Cidália
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2020
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179295/
https://ncbi.nlm.nih.gov/pubmed/31932372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01651-19
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