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Fluconazole and Voriconazole Resistance in Candida parapsilosis Is Conferred by Gain-of-Function Mutations in MRR1 Transcription Factor Gene

Candida parapsilosis is the second most prevalent fungal agent causing bloodstream infections. Nevertheless, there is little information about the molecular mechanisms underlying azole resistance in this species. Mutations (G1747A, A2619C, and A3191C) in the MRR1 transcription factor gene were ident...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Branco, Joana, Silva, Ana P., Silva, Raquel M., Silva-Dias, Ana, Pina-Vaz, Cidália, Butler, Geraldine, Rodrigues, Acácio G., Miranda, Isabel M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576118/
https://ncbi.nlm.nih.gov/pubmed/26248365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00842-15
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