Fluconazole and Voriconazole Resistance in Candida parapsilosis Is Conferred by Gain-of-Function Mutations in MRR1 Transcription Factor Gene

Candida parapsilosis is the second most prevalent fungal agent causing bloodstream infections. Nevertheless, there is little information about the molecular mechanisms underlying azole resistance in this species. Mutations (G1747A, A2619C, and A3191C) in the MRR1 transcription factor gene were ident...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Branco, Joana, Silva, Ana P., Silva, Raquel M., Silva-Dias, Ana, Pina-Vaz, Cidália, Butler, Geraldine, Rodrigues, Acácio G., Miranda, Isabel M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Mechanisms of Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576118/
https://ncbi.nlm.nih.gov/pubmed/26248365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00842-15
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