Ibuprofen Potentiates the In Vivo Antifungal Activity of Fluconazole against Candida albicans Murine Infection

Candida albicans is the most prevalent cause of fungemia worldwide. Its ability to develop resistance in patients receiving azole antifungal therapy is well documented. In a murine model of systemic infection, we show that ibuprofen potentiates fluconazole antifungal activity against a fluconazole-r...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Costa-de-Oliveira, Sofia, Miranda, Isabel M., Silva-Dias, Ana, Silva, Ana P., Rodrigues, Acácio G., Pina-Vaz, Cidália
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468673/
https://ncbi.nlm.nih.gov/pubmed/25845879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05056-14
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