Genetic Basis for Differential Activities of Fluconazole and Voriconazole against Candida krusei

Invasive infections caused by Candida krusei are a significant concern because this organism is intrinsically resistant to fluconazole. Voriconazole is more active than fluconazole against C. krusei in vitro. One mechanism of fluconazole resistance in C. krusei is diminished sensitivity of the targe...

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Detalhes bibliográficos
Main Authors: Fukuoka, Takashi, Johnston, Douglas A., Winslow, Carol A., de Groot, Marcel J., Burt, Catherine, Hitchcock, Christopher A., Filler, Scott G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152512/
https://ncbi.nlm.nih.gov/pubmed/12654649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1213-1219.2003
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