Genetic Basis for Differential Activities of Fluconazole and Voriconazole against Candida krusei

Invasive infections caused by Candida krusei are a significant concern because this organism is intrinsically resistant to fluconazole. Voriconazole is more active than fluconazole against C. krusei in vitro. One mechanism of fluconazole resistance in C. krusei is diminished sensitivity of the targe...

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izdano v:	Antimicrob Agents Chemother
Principais autores:	Fukuoka, Takashi, Johnston, Douglas A., Winslow, Carol A., de Groot, Marcel J., Burt, Catherine, Hitchcock, Christopher A., Filler, Scott G.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2003
Teme:	Mechanisms of Resistance
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152512/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654649/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.4.1213-1219.2003
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