Fluconazole Resistance Associated with Drug Efflux and Increased Transcription of a Drug Transporter Gene, PDH1, in Candida glabrata

Sequential Candida glabrata isolates were obtained from the mouth of a patient infected with human immunodeficiency virus type 1 who was receiving high doses of fluconazole for oropharyngeal thrush. Fluconazole-susceptible colonies were replaced by resistant colonies that exhibited both increased fl...

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Bibliografski detalji
Glavni autori: Miyazaki, Haruko, Miyazaki, Yoshitsugu, Geber, Antonia, Parkinson, Tanya, Hitchcock, Christopher, Falconer, Derek J., Ward, Douglas J., Marsden, Katherine, Bennett, John E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Mechanisms of Action: Physiological Effects
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC105668/
https://ncbi.nlm.nih.gov/pubmed/9661006
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