Fluconazole Resistance Associated with Drug Efflux and Increased Transcription of a Drug Transporter Gene, PDH1, in Candida glabrata

Sequential Candida glabrata isolates were obtained from the mouth of a patient infected with human immunodeficiency virus type 1 who was receiving high doses of fluconazole for oropharyngeal thrush. Fluconazole-susceptible colonies were replaced by resistant colonies that exhibited both increased fl...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Miyazaki, Haruko, Miyazaki, Yoshitsugu, Geber, Antonia, Parkinson, Tanya, Hitchcock, Christopher, Falconer, Derek J., Ward, Douglas J., Marsden, Katherine, Bennett, John E.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Mechanisms of Action: Physiological Effects
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105668/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9661006/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.7.1695
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