Fluconazole Resistance Associated with Drug Efflux and Increased Transcription of a Drug Transporter Gene, PDH1, in Candida glabrata

Sequential Candida glabrata isolates were obtained from the mouth of a patient infected with human immunodeficiency virus type 1 who was receiving high doses of fluconazole for oropharyngeal thrush. Fluconazole-susceptible colonies were replaced by resistant colonies that exhibited both increased fl...

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Main Authors: Miyazaki, Haruko, Miyazaki, Yoshitsugu, Geber, Antonia, Parkinson, Tanya, Hitchcock, Christopher, Falconer, Derek J., Ward, Douglas J., Marsden, Katherine, Bennett, John E.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1998
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Mechanisms of Action: Physiological Effects
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC105668/
https://ncbi.nlm.nih.gov/pubmed/9661006
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