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Genetic Basis for Differential Activities of Fluconazole and Voriconazole against Candida krusei

Invasive infections caused by Candida krusei are a significant concern because this organism is intrinsically resistant to fluconazole. Voriconazole is more active than fluconazole against C. krusei in vitro. One mechanism of fluconazole resistance in C. krusei is diminished sensitivity of the targe...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Fukuoka, Takashi, Johnston, Douglas A., Winslow, Carol A., de Groot, Marcel J., Burt, Catherine, Hitchcock, Christopher A., Filler, Scott G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2003
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152512/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.4.1213-1219.2003
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