An analysis of MIF structural features that control functional activation of CD74

For more than fifteen years, the tautomerase active site of macrophage migration inhibitory factor (MIF) and its catalytic residue Pro1 have been being targeted for the development of therapeutics that block activation of its cell surface receptor, CD74. Neither the biological role of the MIF cataly...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chem Biol
Egile Nagusiak: Pantouris, Georgios, Syed, Mansoor Ali, Fan, Chengpeng, Rajasekaran, Deepa, Cho, Thomas Yoonsang, Rosenberg, Eric M., Bucala, Richard, Bhandari, Vineet, Lolis, Elias J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575896/
https://ncbi.nlm.nih.gov/pubmed/26364929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.08.006
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