An analysis of MIF structural features that control functional activation of CD74

For more than fifteen years, the tautomerase active site of macrophage migration inhibitory factor (MIF) and its catalytic residue Pro1 have been being targeted for the development of therapeutics that block activation of its cell surface receptor, CD74. Neither the biological role of the MIF cataly...

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Publicado en:Chem Biol
Main Authors: Pantouris, Georgios, Syed, Mansoor Ali, Fan, Chengpeng, Rajasekaran, Deepa, Cho, Thomas Yoonsang, Rosenberg, Eric M., Bucala, Richard, Bhandari, Vineet, Lolis, Elias J.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575896/
https://ncbi.nlm.nih.gov/pubmed/26364929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.08.006
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