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An analysis of MIF structural features that control functional activation of CD74

For more than fifteen years, the tautomerase active site of macrophage migration inhibitory factor (MIF) and its catalytic residue Pro1 have been being targeted for the development of therapeutics that block activation of its cell surface receptor, CD74. Neither the biological role of the MIF cataly...

詳細記述

保存先:
書誌詳細
出版年:Chem Biol
主要な著者: Pantouris, Georgios, Syed, Mansoor Ali, Fan, Chengpeng, Rajasekaran, Deepa, Cho, Thomas Yoonsang, Rosenberg, Eric M., Bucala, Richard, Bhandari, Vineet, Lolis, Elias J.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575896/
https://ncbi.nlm.nih.gov/pubmed/26364929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.08.006
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