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An analysis of MIF structural features that control functional activation of CD74
For more than fifteen years, the tautomerase active site of macrophage migration inhibitory factor (MIF) and its catalytic residue Pro1 have been being targeted for the development of therapeutics that block activation of its cell surface receptor, CD74. Neither the biological role of the MIF cataly...
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| 出版年: | Chem Biol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4575896/ https://ncbi.nlm.nih.gov/pubmed/26364929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.08.006 |
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